The Performance Probiotic
Nella™
Decoded from elite athletes. Clinically validated for gut health, restorative sleep, and sustained daily energy.
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What Nella does
Gut, Immune, and Brain Benefits.
All in one daily capsule.
Nella targets the gut-immune axis — the biological pathway that connects your microbiome to immune function, sleep architecture, and cellular energy.
Gut-Immune Restoration
Nella's proprietary strains — decoded from elite athletes — re-seed the gut with organisms that regulate the gut-immune barrier. Consistent digestion, reduced bloating, and restored microbiome diversity within the first week.
Restorative Sleep
The gut-brain axis directly regulates circadian rhythm and sleep architecture. Nella's strains modulate this pathway — users report faster sleep onset, fewer night wakings, and deeper recovery.
Sustained Daily Energy
No caffeine. No crash. Nella supports the short-chain fatty acid production that fuels your cells metabolically — creating a consistent energy baseline that builds over weeks, not hours.
The mechanism
How Nella works inside your gut
Nella contains keystone bacterial strains decoded from elite athletes that promote beneficial gut flora — aiding digestion for better nutrient absorption and metabolism. Packed in an acid-resistant delayed-release capsule, Nella reaches your gut intact to do its job.
Nella reduces reactive oxygen species and inflammatory cytokines — including IL-6 biomarkers — to support significant improvements in sleep quality. It also improves the free testosterone to cortisol ratio, critical for recovery and deep, restorative sleep.
Nella provides a natural boost in energy by increasing the biosynthesis of Vitamin K and antioxidant production. This helps your body improve resilience to stressors — elevating energy from the inside out, not through stimulants.
Harvard Medical School · Wyss Institute
The research that made Nella possible.
In 2022, Nella was developed from four years of isolation, cultivation, and IRB-approved clinical validation. Published in Microbiome. After sequencing the gut microbiomes of ultra-marathon runners and discovering a class of microorganisms uniquely enriched post-exercise in elite athletes, nearly absent in sedentary individuals.
Real results
What 40,000+ people are saying.
I'm a 50 year old athletic woman — hiking, biking, running. I feel amazing on this product. Specifically I have no bloating, I sleep through the night. Energy-wise I have no jittery feeling. After an 8 mile mountain bike ride I feel like I could run a 5K.
I gave Nella a try, and by Day 3 I felt a remarkable difference — my emotions grew more balanced, nighttime sleepiness became stronger, deep sleep increased significantly, and mornings were no longer accompanied by fatigue. Thank you, Nella!
As an ultra distance runner, triathlete, and business owner, I'm always looking for best-in-class supplements. Nella has given me better results after only a few weeks than 5+ different probiotics I've used previously. I'm sleeping better, recovering faster, have more energy and feel my body working the way it should.
After two months of use, gut health is much improved. I have much more energy and a noticeable improvement in sleep. Plan to continue using Nella.
I've been struggling with bad sleep and gut health due to SIBO. Taking Nella has completely solved my motility and sleep quality. I fall asleep and stay asleep — honestly in disbelief. The first of many I've tried that actually works.
As a physician I was pleasantly surprised to see not only improvements at the digestive level, but also positive changes in exercise tolerance, lesser exhaustion and muscle fatigue, and progressive improvement in sleep. The clinical data is real.
I have IBS and CFS for nearly 20 years and decided to give Nella a try. The difference to my IBS has been utterly life changing. It's beyond brilliant. My gut health has transformed and my energy is genuinely better.
Having an auto-immune disease, gut health research has always caught my attention. It wasn't until I switched to Nella that I saw significant benefits — less inflammation, better sleep, more endurance. I've recommended it to my rheumatologist.
What to expect
A biological shift takes time.
Nella's strains begin establishing in your gut. Subtle changes in digestion and regularity as your microbiome begins to shift.
Bloating decreases. Digestion becomes consistent. Many notice improved energy as gut-immune signaling improves.
The gut-brain axis shifts. Sleep onset faster, fewer night wakings, waking more rested. Energy becomes reliable.
Your microbiome has fully integrated Nella's strains. Sustained energy, deep sleep, and gut health are your new biological baseline.
Why Nella is different
Not all probiotics are created equal.
The difference? It's where the strains came from and whether anyone actually tested if they work. We can point to the athlete, the lab, and the published paper.
Comparisons reflect typical, publicly available product and ingredient information. Individual brands vary.
Complete the system
Pair Nella with V·Nella for full-spectrum gut performance.
Nella handles the gut-immune axis — sleep, digestion, and energy baseline. V·Nella handles the gut-muscle axis — endurance, lactic acid conversion, and sustained output. Together they cover every dimension of what your microbiome can do. Save $45 with the Health Bundle.