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Our Science

Creating the new frontier of health and wellness

The key to better health is in your gut.

We are as much bacteria as we are human - trillions of microorganisms in and on our body, most residing in our gut. We have 100x more bacterial genes in our body than we do human genes. The microbial ecosystem, known as our microbiome, greatly affects our development, functionality, and health. Much of our microbiome is shaped by diet, environmental exposure, antibiotic consumption, geography, and physical activity.

"We decode the top 0.01% of the human population to identify the 0.1% of the microbiome that drives human health."

-Jonathan Scheiman, Founder & CEO

Decoding Elite Microbiomes (Guts)

TO UNLOCK OPTIMAL PERFORMANCE

Years of Science-Led Research

We developed our athlete microbiome technology at the Wyss Institute for Biologically Inspired Engineering, at Harvard. We are big believers in form fits function and taking a cue from natural selection - seeing what works in super performers to support their physiological demands and then applying those learnings to develop novel nutrition modalities. This process entails extracting bacterial genetic information from microbiome samples for next-generation sequencing and bioinformatic analysis. We then assess athlete microbiome compositions - how they compare to non-athletes, how they differ between athletes from other sports and how they change over time. We look to identify strains that are unique or enriched in athletes, or that change over time between performance and recovery phases. Once identified, we use microbiology and culturomics techniques to purify, validate, and develop our strains for functional testing and commercialization. However, we’re not done. We discovered that the strain Veillonella increases in abundance in ultra-marathon runners post-race (Nature Medicine). This specific strain offers a heightened ability to process lactic acid and in turn may offer endurance benefits.

Featured in National Geographic Explorer

The microbiome is the epicenter of health and wellness.

WATCH NOW

SCIENTIFIC REFERENCES

Gut Fit Challenge: FITBIOMICS 2-week Beta Test

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Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism

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Discovery of performance-enhancing bacteria in the human microbiome

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Harvard’s athlete-based next-generation probiotics technology licensed to FitBiomics

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International Society of Sports Nutrition Position Stand: Probiotics

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The athletic gut microbiota

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It takes quite a lot of work to prove a cause-and-effect relationship between specific microbes and health or fitness. Here at FITBIOMICS, we'd like to share and engage the public in the full process from hypothesis to discovery - ranging from sequencing athlete microbiomes to animal testing to human clinical trials. Unlike pharmaceuticals, nutritional supplements and probiotics do not require double-blind placebo-controlled randomized clinical trials (DBPCRCT), but we'd like to see such evidence grow and see profits from products go to support continued research. Ideally, we want DBPCRCT on humans with an adequate study design to achieve statistical significance. As a startup, we push to evaluate our products for all safety, quality, and efficacy measures beyond what is mandated. This allows us to understand the metabolomics and human perceived benefits of our probiotics before launching while continuing to pursue IRB-approved clinical trials.

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